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NEW Nature Made SAM-e Double Strength, 400mg Tablets 12 ea 29 of 29 people found the following review helpful: sam-e worked for me, August 5, 1999 Reviewer: A reader from Brooklyn, New York I took Dr. Brown's advice and used sam-e. I had had some success in treating my chronic depression with wellbutrin, but oppressive feelings of sadness, and self-destructive ideation, remained. One week of 200mg sam-e two times daily and the oppressive feelings began to lessen. In two weeks the bad feelings had remitted completely. Though effective, sam-e was mild in its action -- I did not feel that I had been clubbed by a mega-drug. Feeling well, I am able now to have better insight into life problems linked to my long depression -- and I'm able to work on repairing family relationships that had been damaged. I recommend that anyone suffering from depression try sam-e. Reading Dr. Brown's book is an excellent way to learn about this substance.

SAM-e (S-adenosylmethionine) is a naturally occurring compound found in all living organisms.  In humans, SAM-e is distributed throughout the body and is involved in many important biochemical reactions.  SAM-e is critical in the manufacture of joint cartilage and in the maintenance of neural cell membrane function.  Because significant amount of SAM-e are not readily available through the diet, the body is responsible for making its own SAM-e.  Scientists know that certain groups of people, including the elderly, have low levels of SAM-e in their bodies.  For many reasons, it is important to maintain proper levels of SAM-e in the body.  Numerous clinical studies involving thousands of people indicate that supplementation with SAM-e supports and promotes the health of a multitude of body functions including:

• Joint Health, Mobility and Joint Comfort*
• Mood and Emotional Well-being*
• Liver Health*

SAM-e is popular in Europe where doctors have administered it for over 20 years.  The benefits of SAM-e have been demonstrated by its long term use.  Actimet™, the stable and bio-available form SAM-e, is now available in the U.S. mass market as a dietary supplement - only from Nature Made.

Short and long term clinical studies show that SAM-e is a very safe and non-toxic product.

Ingredients:

S-adenosylmethionine 1,4 butanedisulfonate, Cellulose, Sodium Starch Glycolate, Methacrylic Acid Copolymer, Talc, Polyethylene Glycol, Silica, Magnesium Stearate, Polysorbate 80, Sodium Hydroxide, Iron Oxide, Simethicone

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any disease.